Objective: Parkinson’s disease (PD) is a progressive neurological disorder characterised by a large number of motor and non-motor features that can impact on function to a variable degree. This review ...

Three patients are described who developed a severe neuropathy after chemotherapy with high dosecis-diamine-(1,1-cyclobutane dicarboxylato) platinum (carboplatin). This toxic side effect, which is ...

Background Young onset atypical parkinsonism with dementia is a relatively uncommon clinical pres- entation, and identifying an underlying aetiology can be elusive. Case Presentation We present a 43 ...

Background: The visual association test (VAT) is a brief learning task based on imagery mnemonics. The test materials consist of six line drawings of pairs of interacting objects or animals—for ...

Background Corticospinal tract (CST) degeneration and cortical atrophy are consistent features of amyotrophic lateral sclerosis (ALS). We hypothesised that neurite orientation dispersion and density ...

1 Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA 2 Penn Memory Center, Perelman School of Medicine at the University of ...

A staging scheme based on ophthalmoscopic signs of disturbed axoplasmic transport is described. A study employing fundus photographs showed good reproducibility among different observers. Specificity ...

Correspondence to Dr Ding Ding, Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan Univeristy, Shanghai 200040, China; dingding{at}huashan.org.cn We have ...

2 Jubilee Day Hospital, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear NE29 8NH, UK 3 North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, UK ...

OBJECTIVES To evaluate, in people with multiple sclerosis, two psychometric assumptions that must be satisfied for valid use of the medical outcomes study 36-item short form health survey (SF-36): the ...

Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

Background: Prompt assessment and investigation of transient ischaemic attack (TIA) followed by early initiation of secondary prevention is effective in reducing recurrent stroke. Nevertheless, many ...