blocker approved for the treatment of chronic inflammatory demyelinating polyneuropathy or CIDP. CIDP is a progressive, immune-mediated rare and debilitating neuromuscular disorder of the peripheral ...
Vertex announces data from a phase II study evaluating its NaV1.8 pain signal inhibitor, suzetrigine, for treating painful lumbosacral radiculopathy. Shares down.
Lack of NaV1.7 activity leads to the inability to sense pain, whereas NaV1.7 gain of function leads to severe pain. Modulation of NaV1.7, therefore, should be an effective mechanism for decreasing ...