Pain is one of the most debilitating symptoms that presents with neuropathy. Neuropathic pain syndrome is a challenge to treat and, even with appropriate evidence-based treatment, only a 40% ...
Spinal cord injury (SCI) remains one of the most devastating medical conditions, severely impacting quality of life and often ...
They describe neuropathic pain as a neuroimmune disorder, involving activation of Schwann cells, microglia and astrocytes in a complex temporal and spatial pattern. Blocking the signaling pathways ...
Astrocytes are tiny, star-shaped cells that support nerve cells in the brain and were previously thought to serve only this supportive role. The lateral septum, a part of the brain, plays the role ...
In particular, astrocytes and microglia are the immunocompetent ... glial-neuron interactions for such indications as neuropathic pain. According to Dartmouth's DeLeo—who has been working ...
Astrocytes are tiny, star-shaped cells that support nerve cells in the brain and were previously thought to serve only this supportive role. The lateral septum, a part of the brain, plays the role ...
On the other hand, one symptom, cold allodynia for example, can be the result of various mechanisms in peripheral or central neuropathic pain. [25] Another point that is important to discuss is ...