Research has shown a link between an increased risk of dementia and long-term use of Benadryl and other anticholinergic drugs that block ... off-label for chronic pain, insomnia and obsessive ...

And each year, according to a recent Public Health England report, about five million are prescribed opioids - painkillers that can be as powerful as Class A drugs ... for long-term pain will ...

People with chronic pain are being ... "shocking" lack of long-term data, even though the pills are usually prescribed for many months. But patients are advised to stay on medication if it works ...