San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

The 49ers injury woes continue at running back after Isaac Guerendo was carted off the field in the 1st quarter.

The San Francisco 49ers are set to take on the Arizona Cardinals, with Josh Dobbs set to make his first career start for the ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started ...

The San Francisco 49ers entered Sunday's season finale against the Arizona Cardinals with a depleted roster. Quarterback Josh Dobbs took the reins in place ...

ARLINGTON, Texas — Trey Lance started at quarterback for the Dallas Cowboys against the Washington Commanders on Sunday, his ...

Marcus Mariota threw a 5-yard touchdown pass to Terry McLaurin with 3 seconds left, lifting Washington to a 23-19 victory ...

Arizona Cardinals OLB Zaven Collins needs one sack to reach a $300,000 incentive in his contract today against the San Francisco 49ers. Collins would reach five sacks on the season with the ...

In the season opener, the Eagles found success underneath, with Jalen Hurts completing 16 of 18 passes for 155 of his 278 ...

Watch Houston Texans running back Dameon Pierce's best plays from career-high 176-yard game during Week 18 of the 2024 season.

Dallas Cowboys quarterback Trey Lance and New England Patriots signal-caller Joe Milton both got home starts on Sunday in their teams' final ...