Linaclotide, a guanylate cyclase C receptor agonist, has shown promising efficacy as a treatment for chronic constipation in a phase IIb, double-blinded, placebo-controlled, dose-ranging trial.

Constipation is a common and often chronic disorder, with multiple symptoms for which few treatment strategies have proven effective. The goal of treatment for patients with chronic constipation ...

More recently, newer agents have been approved for the treatment of patients with chronic constipation on the basis of comprehensive clinical investigation programs. Tegaserod, with its well ...

Chronic constipation may stem from various causes beyond diet and lifestyle. Recognising and addressing the hidden factors, ...

The safety and efficacy of this drug for the treatment of constipation was demonstrated in clinical trials, and in 2006, the FDA approved lubiprostone (Amitiza ®, Sucampo Pharmaceuticals, Inc ...

When it becomes more chronic, we need to ... And so once that's in place, if the constipation becomes more severe, we start to look at various types of treatments. The kinds of things that we ...

Common causes for this include: Certain gastrointestinal, neurologic, metabolic, and even psychiatric conditions are associated with chronic constipation, including: The treatment of constipation ...

Constipation can make you feel constantly bloated or uncomfortable. You may also experience harmful side effects, such as bowel obstructions, due to chronic ... in pregnant women and women at ...

Constipation is a difficulty passing stool. Chronic constipation occurs when the problem lasts for more than a few weeks. Most people experience mild cases of constipation on occasion and treat it ...

Chronic constipation is a condition characterized by persistent difficulty in passing stool and infrequent bowel movements.

Chronic constipation ... or abdominal pain alongside constipation warrants immediate medical attention. Early screening and diagnosis are crucial for effective treatment. While constipation ...

Chronic constipation can be exacerbated by daily habits like excessive tea drinking and smoking. Tea, especially black tea, contains tannins and caffeine, which can dehydrate the body and slow ...