Proper survival and regeneration of retinal ganglion cells (RGCs), which constitute the optic nerve, is crucial for managing traumatic or ischemic optic nerve injury, optic neuropathy, or optic ...

Cell replacement therapy offers a therapeutic approach for patients with advanced disease in which there has been loss of photoreceptors, RPE or retinal ganglion cells (RGCs). Age-related macular ...

Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model ...

Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, ...

While diabetic retinopathy is typically associated with vascular damage, recent work has shown that the density of retinal ganglion cells is also reduced in diabetes prior to the development of ...

USC researchers use 3D microscopy and genetically engineered viruses to visualize and distinguish specific retinal ganglion cell types (shown here in green) from other cells in the retina (purple).

The trial is designed to assess the tolerability, efficacy, and safety of two different dosages of the therapy.

In the tadpole stage, the eyes are lateral and all ganglion cells project axons to the contralateral side of the brain (retina is denoted by curves, ganglion cell axons are denoted by lines).

Patients with fibromyalgia experienced changes in the macular ganglion cell layer and retinal nerve fiber layer.