A single-center retrospective study in China found a significant association between pain duration and intensity in patients ...
Animal models are critical in improving our understanding of neuropathic pain processes, enabling the discovery and development of new pain management medicines. This study evaluated behavioral ...
including validated neuropathic pain disease models. In parallel with the submission, the company is conducting a neurotoxicity study, as required by the FDA’s written feedback, to support the ...
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Scientists discover new receptor for nerve growth factor—a promising target for treating painPeach et al, Neuropilin-1 inhibition suppresses nerve-growth factor signaling and nociception in pain models, Journal of Clinical Investigation (2024). DOI: 10.1172/JCI183873 ...
The IND application includes comprehensive data and reports detailing Ketamir-2's pharmacology, pharmacokinetics, and toxicology, along with results from both in vitro and in vivo studies, including ...
fully normalizing pain thresholds in validated neuropathic pain models. Furthermore, Ketamir-2 has shown a strong safety and toxicological profile, observed across cardiovascular, CNS, respiratory ...
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