Although some individuals may benefit from increasing their fiber intake, this approach may make symptoms worse in patients with severe constipation. It is commonly believed that increasing fluid ...
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Water absorption is increased which leads to hard stool and difficulty completing the prescribed bowel program. Constipation is often exacerbated by increased use of prescription medications ...
Background: Methylnaltrexone has been shown to be effective for treating opioid-induced constipation (OIC) in chronic settings, but its effects on acute OIC have not been studied. Objective ...
This pilot study suggests that methylnaltrexone actively induces laxation and is generally well tolerated in patients receiving mu-opioid analgesia, following orthopedic surgery, who develop OIC ...